Medications


Eliglustat oral capsules

What is this medicine?

ELIGLUSTAT (el i GLOO stat) is used for the long-term treatment of adults with Gaucher disease type I. Eliglustat is not used in certain people with Gaucher disease type 1. Your doctor will perform a test to make sure this medicine is right for you.

How should I use this medicine?

Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. Do not cut, crush, or chew this medicine. Do not take with grapefruit juice. You can take it with or without food. If it upsets your stomach, take it with food. Take your medicine at regular intervals. Do no take it more often than directed. Do not stop taking except on your doctor's advice.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:

  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue

  • signs and symptoms of a dangerous change in heartbeat or heart rhythm like chest pain; dizziness; fast or irregular heart beat; palpitations; feeling faint or lightheaded, falls; breathing problems

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • diarrhea

  • headache

  • nausea

  • pain in the arms, legs, or back

  • stomach pain

  • tiredness

What may interact with this medicine?

Do not take this medicine with any of the following medications:

  • cisapride

  • dofetilide

  • dronedarone

  • grapefruit juice

  • pimozide

  • quinidine

  • quinine

  • ritonavir

  • saquinavir

  • tipranavir

  • thioridazine

  • ziprasidone

This medicine may also interact with the following medications:

  • antiviral medicines for HIV or AIDS

  • certain medicines for blood pressure, heart disease, irregular heart beat

  • certain medicines for depression, anxiety, or psychotic disturbances

  • certain medicines for fungal infections like ketoconazole and itraconazole

  • certain medicines for seizures like carbamazepine, phenobarbital, phenytoin

  • colchicine

  • dabigatran

  • digoxin

  • other medicines that prolong the QT interval (cause an abnormal heart rhythm)

  • phenothiazines like chlorpromazine, mesoridazine, prochlorperazine, thioridazine

  • ranitidine

  • rifampin

  • St. John's Wort

What if I miss a dose?

If you miss a dose, take the next dose at the usual time. Do not take double or extra doses.

Where should I keep my medicine?

Keep out of the reach of children.

Store between 20 and 25 degrees C (68 and 77 degrees F). Throw away any unused medicine after the expiration date.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

  • heart disease

  • history of heart attack

  • history of irregular heartbeat

  • kidney disease

  • liver disease

  • an unusual or allergic reaction to eliglustat, other medicines, foods, dyes, or preservatives

  • pregnant or trying to get pregnant

  • breast-feeding

What should I watch for while using this medicine?

Tell your doctor or healthcare professional if your symptoms do not start to get better or if they get worse.

Certain genetic factors may reduce the effect of this medicine. Your doctor may use genetic tests to determine treatment.


NOTE:This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider. Copyright© 2017 Elsevier
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