Medications


Chlorpheniramine; Codeine immediate-release oral suspension

What is this medicine?

CHLORPHENIRAMINE; CODEINE (klor fen IR a meen; KOE deen) is a combination of an antihistamine and cough suppressant. It is used to treat the symptoms of cough, allergies, and colds.

How should I use this medicine?

Take this medicine by mouth with a glass of water. You can take it with or without food. If it upsets your stomach, take it with food. Follow the directions on the product label. Shake well before using. Use a specially marked spoon or container to measure your medicine. Household spoons are not accurate. Take your doses at regular intervals. Do not take your medicine more often than directed.

Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for selected conditions in children as young as 2 years, precautions do apply.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:

  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue

  • anxious

  • breathing problems

  • changes in vision

  • chest tightness

  • confusion

  • depressed mood

  • feeling faint or lightheaded, falls

  • trouble passing urine or change in the amount of urine

  • unusually slow heartbeat

  • unusually weak or tired

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • constipation

  • dry throat

  • headache

  • nausea

  • stomach upset

What may interact with this medicine?

  • alcohol

  • antihistamines for allergy, cough and cold

  • atropine

  • barbiturate medicines for sleep or seizures

  • certain medicines for bladder problems like oxybutynin, tolterodine

  • certain medicines for stomach problems like dicyclomine, hyoscyamine

  • certain medicines for travel sickness like scopolamine

  • certain medicines for Parkinson's disease like benztropine, trihexyphenidyl

  • ipratropium

  • MAOIs like Carbex, Eldepryl, Marplan, Nardil, and Parnate

  • medicines for depression, anxiety, or psychotic disturbances

  • medicines for sleep

  • muscle relaxants

  • naltrexone

  • narcotic medicines for pain

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

Where should I keep my medicine?

Keep out of the reach of children. This medicine can be abused. Keep your medicine in a safe place to protect it from theft. Do not share this medicine with anyone. Selling or giving away this medicine is dangerous and against the law.

Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F). Do not freeze. Keep container tightly closed. Throw away any unused medicine after the expiration date. Discard unused medicine and used packaging carefully. Pets and children can be harmed if they find used or lost packages.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

  • head injury

  • history of a drug or alcohol abuse problem

  • kidney disease

  • liver disease

  • lung or breathing disease, like asthma

  • other chronic illness

  • prostate disease

  • stomach or intestine problems

  • thyroid disease

  • an unusual or allergic reaction to chlorpheniramine, codeine, other pain medicines, foods, dyes or preservatives

  • pregnant or trying to get pregnant

  • breast-feeding

What should I watch for while using this medicine?

Use exactly as directed by your doctor or health care professional. Do not take more than the recommended dose. You may develop tolerance to this medicine if you take it for a long time. Tolerance means that you will get less cough relief with time. Tell your doctor or health care professional if your symptoms do not improve or if they get worse.

If you have been taking this medicine for a long time, do not suddenly stop taking it because you may develop a severe reaction. Your body becomes used to the medicine. This does NOT mean you are addicted. Addiction is a behavior related to getting and using a drug for a nonmedical reason. If your doctor wants you to stop the medicine, the dose will be slowly lowered over time to avoid any side effects.

You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol may interfere with the effect of this medicine. Avoid alcoholic drinks.

Children may be at higher risk for side effects. If your child has slow breathing, noisy breathing, confusion, or unusual sleepiness, stop giving this medicine and get medical help right away.

The medicine will cause constipation. Try to have a bowel movement at least every 2 to 3 days. If you do not have a bowel movement for 3 days, call your doctor or health care professional.

This medicine may cause dry eyes and blurred vision. If you wear contact lenses you may feel some discomfort. Lubricating drops may help. See your eye doctor if the problem does not go away or is severe.

Immediately call your physician or get emergency help if you are breast-feeding and your baby is sleepier than usual, is limp, or has difficulty breastfeeding or breathing.


NOTE:This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider. Copyright© 2017 Elsevier
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