Medications


Sarilumab injection

What is this medicine?

SARILUMAB (sar IL ue mab) is used to treat adults with rheumatoid arthritis (RA). This medicine helps reduce joint pain and swelling. This medicine is often used with other medicines.

How should I use this medicine?

This medicine is for injection under the skin. You will be taught how to prepare and give this medicine. Use exactly as directed. Take your medicine at regular intervals. Do not take your medicine more often than directed.

It is important that you put your used needles and syringes in a special sharps container. Do not put them in a trash can. If you do not have a sharps container, call your pharmacist of healthcare provider to get one.

A special MedGuide will be given to you by the pharmacist with each prescription and refill. Be sure to read this information carefully each time.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:

  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue

  • breathing problems

  • feeling faint or lightheaded, falls

  • fever or chills, sore throat

  • stomach pain

  • unusual bleeding or bruising

  • yellowing of the eyes or skin

Side effects that usually do not require medical attention (report these to your doctor or health care professional if they continue or are bothersome):

  • pain, redness, or irritation at site where injected

What may interact with this medicine?

Do not take this medicine with any of the following medications:

  • live virus vaccines

This medicine may also interact with the following medications:

  • abatacept

  • adalimumab

  • anakinra

  • atorvastatin

  • certolizumab

  • etanercept

  • golimumab

  • infliximab

  • lovastatin

  • medicines that lower the immune system

  • ofatumumab

  • oral contraceptives

  • rituximab

  • steroid medicines like prednisone or cortisone

  • theophylline

  • tocilizumab

  • tofacitinib

  • warfarin

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

Where should I keep my medicine?

Keep out of the reach of children.

Store in the refrigerator at 2 to 8 degrees C (36 to 46 degrees F). Do not freeze. Store in the original carton until use and protect from light. This injection may be stored at room temperature up to 25 degrees C (77 degrees F) for up to 14 days in the original carton. Throw away any unused medicine after the expiration date on the label.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

  • cancer

  • diabetes

  • diverticulitis

  • having surgery

  • hepatitis B or history of hepatitis B infection

  • high cholesterol

  • immune system problems

  • infection (especially a virus infection such as chickenpox, cold sores, or herpes)

  • liver disease

  • low blood counts, like low white cell, platelets, or red cell counts

  • recently received or scheduled to receive a vaccine

  • tuberculosis, a positive skin test for tuberculosis or have recently been in close contact with someone who has tuberculosis

  • an unusual or allergic reaction to sarilumab, other medicines, foods, dyes or preservatives

  • pregnant or trying to get pregnant

  • breast-feeding

What should I watch for while using this medicine?

Tell your doctor or healthcare professional if your symptoms do not start to get better or if they get worse.

You may need blood work done while you are taking this medicine.

You will be tested for tuberculosis (TB) before you start this medicine. If your doctor prescribes any medicines for TB, you should start taking the TB medicine before starting this medicine. Make sure to finish the full course of TB medicine.

Call your doctor or healthcare professional for advice if you get a fever, chills or sore throat, or other symptoms of a cold or flu. Do not treat yourself. This drug decreases your body's ability to fight infections. Try to avoid being around people who are sick.

Talk to your doctor about your risk of cancer. You may be at risk for certain types of cancers if you take this medicine.


NOTE:This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider. Copyright© 2017 Elsevier
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