Medications


Durvalumab injection

What is this medicine?

DURVALUMAB (dur VAL ue mab) is a monoclonal antibody. It is used to treat urothelial cancer.

How should I use this medicine?

This medicine is for infusion into a vein. It is given by a health care professional in a hospital or clinic setting.

A special MedGuide will be given to you before each treatment. Be sure to read this information carefully each time.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:

  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue

  • black, tarry stools

  • bloody or watery diarrhea

  • breathing problems

  • change in emotions or moods

  • change in sex drive

  • changes in vision

  • chest pain or chest tightness

  • chills

  • confusion

  • cough

  • facial flushing

  • fever

  • headache

  • signs and symptoms of high blood sugar such as dizziness; dry mouth; dry skin; fruity breath; nausea; stomach pain; increased hunger or thirst; increased urination

  • signs and symptoms of liver injury like dark yellow or brown urine; general ill feeling or flu-like symptoms; light-colored stools; loss of appetite; nausea; right upper belly pain; unusually weak or tired; yellowing of the eyes or skin

  • stomach pain

  • trouble passing urine or change in the amount of urine

  • weight gain or weight loss

Side effects that usually do not require medical attention (report these to your doctor or health care professional if they continue or are bothersome):

  • bone pain

  • constipation

  • loss of appetite

  • muscle pain

  • nausea

  • swelling of the ankles, feet, hands

  • tiredness

What may interact with this medicine?

Interactions have not been studied.

What if I miss a dose?

It is important not to miss your dose. Call your doctor or health care professional if you are unable to keep an appointment.

Where should I keep my medicine?

This drug is given in a hospital or clinic and will not be stored at home.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

  • diabetes

  • immune system problems

  • infection

  • inflammatory bowel disease

  • kidney disease

  • liver disease

  • lung or breathing disease

  • lupus

  • organ transplant

  • stomach or intestine problems

  • thyroid disease

  • an unusual or allergic reaction to durvalumab, other medicines, foods, dyes, or preservatives

  • pregnant or trying to get pregnant

  • breast-feeding

What should I watch for while using this medicine?

This drug may make you feel generally unwell. Continue your course of treatment even though you feel ill unless your doctor tells you to stop.

You may need blood work done while you are taking this medicine.

Do not become pregnant while taking this medicine or for 3 months after stopping it. Women should inform their doctor if they wish to become pregnant or think they might be pregnant. There is a potential for serious side effects to an unborn child. Talk to your health care professional or pharmacist for more information. Do not breast-feed an infant while taking this medicine or for 3 months after stopping it.


NOTE:This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider. Copyright© 2017 Elsevier
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