Medications


Tiopronin oral tablets

What is this medicine?

TIOPRONIN (tye oh PROE nin) binds with cystine in the body. It is used to prevent kidney stones in patients with cystinuria.

How should I use this medicine?

Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. Take this medicine on an empty stomach, at least 1 hour before or 2 hours after meals. Do not take with food. Take your medicine at regular intervals. Do not take it more often than directed. Do not stop taking except on your doctor's advice.

Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for children as young as 9 years for selected conditions, precautions do apply.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:

  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue

  • breathing problems

  • coughing up blood

  • dizziness

  • fever or chills, sore throat

  • general ill feeling or flu-like symptoms

  • joint pain

  • low blood counts - this medicine may decrease the number of white blood cells, red blood cells and platelets. You may be at increased risk for infections and bleeding

  • mouth sores

  • muscle pain

  • muscle weakness

  • redness, blistering, peeling or loosening of the skin, including inside the mouth

  • swollen or painful glands

  • trouble passing urine or change in the amount of urine

  • unusual bleeding or bruising

  • unusually weak or tired

Side effects that usually do not require medical attention (Report these to your doctor or health care professional if they continue or are bothersome.):

  • change in taste

  • change in smell

  • diarrhea

  • gas

  • nausea

  • tiredness

  • upset stomach

  • wrinkling or thinning of the skin

What may interact with this medicine?

Interactions are not expected.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

Where should I keep my medicine?

Keep out of the reach of children.

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Keep this medicine in the original container. Throw away any unused medicine after the expiration date.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

  • anemia

  • kidney disease

  • low blood counts, like low white cell, platelet, or red cell counts

  • myasthenia gravis

  • an unusual or allergic reaction to tiopronin, other medicines, foods, dyes, or preservatives

  • pregnant or trying to get pregnant

  • breast-feeding

What should I watch for while using this medicine?

Tell your doctor or healthcare professional if your symptoms do not start to get better or if they get worse. You may need blood work and urine tests done while you are taking this medicine.

You may need to be on a special diet while you are taking this medicine. Talk to your doctor about the foods that you eat and the vitamins that you take. Also, ask your doctor how much fluid you need to drink. Drink the recommended amount of fluid each day to stay hydrated and to help prevent kidney stones.


NOTE:This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider. Copyright© 2018 Elsevier
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