Medications


Crizanlizumab injection

What is this medicine?

CRIZANLIZUMAB (KRIZ an LIZ ue mab) is a selectin blocker. This medicine is used to reduce how often sickle cell crises happen.

How should I use this medicine?

This medicine is for infusion into a vein. It is given by a healthcare professional in a hospital or clinic setting.

Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for children as young as 16 years for selected conditions, precautions do apply.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:

  • allergic reactions like skin rash, itching or hives; swelling of the face, lips, or tongue

  • signs and symptoms of an infusion reaction such as fever; chills or shivering; nausea or vomiting; tiredness; dizziness; sweating; shortness of breath or wheezing

Side effects that usually do not require medical attention (report these to your doctor or health care professional if they continue or are bothersome):

  • back pain

  • diarrhea

  • joint pain

  • stomach pain

What may interact with this medicine?

Interactions are not expected.

What if I miss a dose?

Keep appointments for follow-up doses. It is important not to miss your dose. Call your doctor or healthcare professional if you are unable to keep an appointment.

Where should I keep my medicine?

This medicine is given in a hospital or clinic and will not be stored at home.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

  • an unusual or allergic reaction to crizanlizumab, other medicines, foods, dyes or preservatives

  • pregnant or trying to get pregnant

  • breast-feeding

What should I watch for while using this medicine?

Your condition will be monitored carefully while you are receiving this medicine.


NOTE:This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider. Copyright© 2020 Elsevier
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