Medications


Laronidase injection

What is this medicine?

LARONIDASE (la RON i daz) is a drug that is used to replace an enzyme that is missing in patients with some forms of mucopolysaccharidosis I (MPS I). It is used to treat some of the symptoms of the disease. This medicine is not a cure.

How should I use this medicine?

This medicine is for infusion into a vein. It is given by a health care professional in a hospital or clinic setting.

Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for children as young as 6 months old for selected conditions, precautions do apply.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:

  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue

  • breathing problems

  • changes in vision

  • chest pain

  • cough

  • fever

  • swelling of feet or hands

  • flushing

  • low blood pressure

  • pain, tingling, numbness in the hands or feet

  • redness, pain, or swelling at site where injected

  • yellowing of the eyes or skin

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • irritation at site where injected

What may interact with this medicine?

Interactions are not expected.

What if I miss a dose?

It is important not to miss your dose. Call your doctor or health care professional if you are unable to keep an appointment.

Where should I keep my medicine?

This drug is given in a hospital or clinic and will not be stored at home.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

  • an unusual or allergic reaction to laronidase, other medicines, foods, dyes, or preservatives

  • pregnant or trying to get pregnant

  • breast-feeding

What should I watch for while using this medicine?

Your condition will be monitored carefully while you are receiving this medicine.

Visit your doctor for regular checks on your progress. Tell your doctor or healthcare professional if your symptoms do not start to get better or if they get worse.

There is a registry for MPS I patients to better understand the disease and the treatments. Talk to your doctor about signing up with the registry.


NOTE:This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider. Copyright© 2017 Elsevier
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