Medications


Degarelix injection

What is this medicine?

DEGARELIX (deg a REL ix) is used to treat men with advanced prostate cancer.

How should I use this medicine?

This medicine is for injection under the skin. It is usually given by a health care professional in a hospital or clinic setting.

If you get this medicine at home, you will be taught how to prepare and give this medicine. Use exactly as directed. Take your medicine at regular intervals. Do not take it more often than directed.

It is important that you put your used needles and syringes in a special sharps container. Do not put them in a trash can. If you do not have a sharps container, call your pharmacist or healthcare provider to get one.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:

  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue

  • fever or chills

  • irregular heartbeat

  • nausea and vomiting along with severe abdominal pain

  • pain or difficulty passing urine

  • pelvic pain or bloating

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • change in sex drive or performance

  • constipation

  • headache

  • high blood pressure

  • hot flashes (flushing of skin, increased sweating)

  • itching, redness or mild pain at site where injected

  • joint pain

  • trouble sleeping

  • unusually weak or tired

  • weight gain

What may interact with this medicine?

Do not take this medicine with any of the following medications:

  • amiodarone

  • bretylium

  • disopyramide

  • dofetilide

  • droperidol

  • ibutilide

  • procainamide

  • quinidine

  • sotalol

What if I miss a dose?

Try not to miss a dose. If you do miss a dose, call your doctor or health care professional for advice.

Where should I keep my medicine?

Keep out of the reach of children.

This drug is usually given in a hospital or clinic and will not be stored at home.

In rare cases, this medicine may be given at home. If you are using this medicine at home, you will be instructed on how to store this medicine. Throw away any unused medicine after the expiration date on the label.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

  • heart disease

  • kidney disease

  • liver disease

  • low levels of potassium or magnesium in the blood

  • osteoporosis

  • an unusual or allergic reaction to degarelix, mannitol, other medicines, foods, dyes, or preservatives

  • pregnant or trying to get pregnant

  • breast-feeding

What should I watch for while using this medicine?

Visit your doctor or health care professional for regular checks on your progress and discuss any issues before you start taking this medicine.

Do not rub or scratch injection site. There may be a lump at the injection site, or it may be red or sore for a few days after your dose.

Your doctor or health care professional will need to monitor your hormone levels in your blood to check your response to treatment. Try to keep any appointments for testing.


NOTE:This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider. Copyright© 2017 Elsevier
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