Medications


Eribulin solution for injection

What is this medicine?

ERIBULIN (er e bu lin) is a chemotherapy drug. It is used to treat breast cancer and liposarcoma.

How should I use this medicine?

This medicine is for infusion into a vein. It is given by a health care professional in a hospital or clinic setting.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:

  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue

  • low blood counts - this medicine may decrease the number of white blood cells, red blood cells and platelets. You may be at increased risk for infections and bleeding.

  • signs of infection - fever or chills, cough, sore throat, pain or difficulty passing urine

  • signs of decreased platelets or bleeding - bruising, pinpoint red spots on the skin, black, tarry stools, blood in the urine

  • signs of decreased red blood cells - unusually weak or tired, fainting spells, lightheadedness

  • pain, tingling, numbness in the hands or feet

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • constipation

  • hair loss

  • headache

  • loss of appetite

  • muscle or joint pain

  • nausea, vomiting

  • stomach pain

What may interact with this medicine?

Do not take this medicine with any of the following medications:

  • amiodarone

  • astemizole

  • arsenic trioxide

  • bepridil

  • bretylium

  • chloroquine

  • chlorpromazine

  • cisapride

  • clarithromycin

  • dextromethorphan, quinidine

  • disopyramide

  • dofetilide

  • droperidol

  • dronedarone

  • erythromycin

  • grepafloxacin

  • halofantrine

  • haloperidol

  • ibutilide

  • levomethadyl

  • mesoridazine

  • methadone

  • pentamidine

  • procainamide

  • quinidine

  • pimozide

  • posaconazole

  • probucol

  • propafenone

  • saquinavir

  • sotalol

  • sparfloxacin

  • terfenadine

  • thioridazine

  • troleandomycin

  • ziprasidone

What if I miss a dose?

It is important not to miss your dose. Call your doctor or health care professional if you are unable to keep an appointment.

Where should I keep my medicine?

This drug is given in a hospital or clinic and will not be stored at home.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

  • heart disease

  • history of irregular heartbeat

  • kidney disease

  • liver disease

  • low blood counts, like low white cell, platelet, or red cell counts

  • low levels of potassium or magnesium in the blood

  • an unusual or allergic reaction to eribulin, other medicines, foods, dyes, or preservatives

  • pregnant or trying to get pregnant

  • breast-feeding

What should I watch for while using this medicine?

This drug may make you feel generally unwell. This is not uncommon, as chemotherapy can affect healthy cells as well as cancer cells. Report any side effects. Continue your course of treatment even though you feel ill unless your doctor tells you to stop.

Call your doctor or health care professional for advice if you get a fever, chills or sore throat, or other symptoms of a cold or flu. Do not treat yourself. This drug decreases your body's ability to fight infections. Try to avoid being around people who are sick.

This medicine may increase your risk to bruise or bleed. Call your doctor or health care professional if you notice any unusual bleeding.

You may need blood work done while you are taking this medicine.

Do not become pregnant while taking this medicine or for 2 weeks after stopping it. Women should inform their doctor if they wish to become pregnant or think they might be pregnant. Men should not father a child while taking this medicine and for 3.5 months after stopping it. There is a potential for serious side effects to an unborn child. Talk to your health care professional or pharmacist for more information. Do not breast-feed an infant while taking this medicine or for 2 weeks after stopping it.


NOTE:This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider. Copyright© 2017 Elsevier
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